نانو محک بهبود
KEYWORDS Asparagine+ 2-aminothiazole+methylcarbonyls+ one-pot synthesis+ organocatalyst

Asparagine as a Green Organocatalyst for the Synthesis of 2-Aminothiazoles

ABSTRACT
In this research, an efficient method for the one-pot synthesis of
2-aminothiazoles via the reaction of thiourea with methylcarbonyls in
the presence of iodine as an oxidant reagent has been developed
using asparagine as a green organocatalyst at 80 C in DMSO solvent.
Advantages of this efficient method include greener and cleaner
conditions, easy isolation of products, higher purity and excellent yield of
products, and convenient manipulation.


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