نانو محک بهبود
Heterogeneous catalyst +Co3O4/CS/PWA+ Three-component reaction+ Ultrasound irradiation+ Indeno[2ʹ;,1ʹ;:5,6]pyrido[2,3-d]pyrimidine

Ultrasound-promoted an efficient method for the one-pot synthesis of indeno fused pyrido[2,3-d]pyrimidines catalyzed by H3PW12O40 functionalized chitosan@Co3O4 as a novel and green catalyst

a b s t r a c t
A novel magnetically recoverable nanocomposite including Co3O4/chitosan/H3PW12O40 (Co3O4/CS/PWA)
as a heterogeneous catalyst was prepared using a facile synthetic method and characterized by FT-IR,
XRD, SEM, VSM and EDX. A simple, efficient and rapid synthesis of indeno[2ʹ,1ʹ:5,6]pyrido[2,3-d]pyrimidines
was accomplished in excellent yields via one-pot three-component reaction of 1,3-dimethyl-6-
aminouracil, aryl aldehydes and 1,3-indandione in the presence of amount of Co3O4/CS/PWA catalyst
under ultrasound irradiation. Then, the catalyst was recovered with an external magnet and reused
several times without significant loss of reactivity.


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